Ondersteund door de wetenschap
Proceive® is een reeks wetenschappelijk samengestelde supplementen op maat gemaakt voor elke fase van kinderwens, zwangerschap en borstvoeding. Gebaseerd op onderzoek van vruchtbaarheids- en medische experts, met gebruik van een breed scala aan klinische studies, biedt Proceive® de meest functionele, uitgebreide en op bewijs gebaseerde voedingssupplementen voor mannen en vrouwen in elke levensfase. Hieronder volgt een selectie van de vele wetenschappelijke studies die zijn gebruikt bij de ontwikkeling van Proceive®.
The Role of Oxidative Stress and Antioxidants in Male Fertility, Renata Walczak–Jedrzejowska, Jan Karol Wolski, and Jolanta Slowikowska– Hilcze. Cent. European J Urol. 2013; 66(1): 60–67. Published online 2013 Apr 26.
Impact of Oxidative Stress on Female Fertility, Elizabeth H. Ruder, Terryl J. Hartman and Marlene B. Goldman Curr Opin Obstet Gynecol. 2009 Jun; 21(3): 219–222.
Effect of L-carnitine and L-Acetyl-Carnitine in Nutrition Treatment for Male Infertility: A Systematic Review, Zhou X, Liu F, Zhai S, Asia Pac J Clin Nutr. 2007; 1 Suppl 1:383-90.
Use of Multivitamins, Intake of B Vitamins and Risk of Ovulatory Infertility, Jorge E. Chavarro, MD, ScD, Janet W. Rich-Edwards, ScD, MPH, Bernard A. Rosner, PhD, and Walter C. Willett, MD, DrPH. Fertil Steril. 2008 Mar; 89(3): 668–676.
MTHFR 677C>T Polymorphism Increases the Male Infertility Risk: A Meta- AnalysisInvolving 26 Studies, Mancheng Gong, Wenjing Dong, Tingyu He, Zhirong Shi, Guiying Huang, Rui Ren, Sichong Huang, Shaopeng Qiu, and Runqiang Yuan. PLoS One. 2015; 10(3): e0121147. Published online 2015 Mar 20.
TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis, Prashant B. Shambharkar, Mark Bittinger, Brian Latario,ZhaoHui Xiong, Somnath Bandyopadhyay, Vanessa Davis, Victor Lin, Yi Yang Reginald Valdez, and Mark A. Labow. PLoS One, 2015; 10(5): e0127480.
Calcium and Vitamin D: Important at Every Age. NIH (2018). NIH Osteoporosis and Related Bone Diseases National Resource Center. [online] Nih.gov. Available at: https://www.bones.nih.gov/healthinfo/bone/bone-health/nutrition/calcium-and-vitamin-d-important-every-age.
Effects of Selenium, Calcium and Calcium Ionophore on Human Oocytes in Vitro Maturation in a Chemically Defined Medium, Mehri Makki, M.Sc., Elham Saboori, M.Sc., Mohammad Ali Sabbaghi, M.Sc., Raheleh Aram, M.Sc., Mohammad Hasan Fallahian, M.Sc., Fatemeh Peyghambari, Ph.D., Hessam Roustaei, M.D., and Abbas Ahmadi, Ph.D. Iran J Reprod Med. 2012 Jul; 10(4): 343–348.
Can Coenzyme Q10 Supplementation Protect the Ovarian Reserve Against Oxidative Damage? Özcan P, Fıçıcıoğlu C, Kizilkale O, Yesiladali M, Tok OE, Ozkan F, Esrefoglu M. J Assist Reprod Genet. 2016 Sep; 33(9):1223-30.
Coenzyme Q10 Restores Oocyte Mitochondrial Function and Fertility During Reproductive Aging, Ben-Meir A, Burstein E, Borrego-Alvarez A, Chong J, Wong E, Yavorska T, Naranian T, Chi M, Wang Y, Bentov Y, Alexis J, Meriano J, Sung HK, Gasser DL, Moley KH, Hekimi S, Casper RF, Jurisicova A. Aging Cell. 2015 Oct;14(5):887-95.
Coenzyme Q10: The Essential Nutrient, Saini R. J Pharm Bioallied Sci. 2011 Jul;3(3):466-7. doi: 10.4103/0975-7406.84471. PMID: 21966175; PMCID: PMC3178961.
Micronutrient Status in Female University Students: Iron, Zinc, Copper, Selenium, Vitamin B12 and Folate, Flavia Fayet-Moore, Peter Petocz, and Samir Samman Nutrients. 2014 Nov; 6(11): 5103–5116.
Genome-Wide Association Study Identifies Loci Affecting Blood Copper, Selenium and Zinc, David M. Evans, Gu Zhu, Veronica Dy, Andrew C. Heath, Pamela A. F. Madden, John P. Kemp, George McMahon, Beate St Pourcain, Nicholas J. Timpson, Jean Golding, Debbie A. Lawlor, Colin Steer, Grant W. Montgomery, Nicholas G. Martin, George Davey Smith, and John B. Whitfield Hum Mol Genet. 2013 Oct 1; 22(19): 3998–4006.
The Role of Vitamin D in Uterine Fibroid Biology, Soumia Brakta, MD, Justin S. Diamond, BS, Ayman Al-Hendy, MD PhD, Michael P. Diamond, MD, and Sunil K. Halder, PhD. Fertil Steril. 2015 Sep; 104(3): 698– 706. Published online 2015 Jun 13.
Immune Aspects of Female Infertility, Andrea Brazdova, Ph.D, Helene Senechal, Ph.D, Gabriel Peltre,Ph.D, and Pascal Poncet, Ph.D. Int J Fertil Steril. 2016 Apr-Jun; 10(1): 1–10. Relevance of vitamin D in reproduction, Janelle Luk, Saioa Torrealday, Genevieve Neal Perry and Lubna Pal. Hum Reprod. 2012 Oct; 27(10): 3015–3027. Published online 2012 Jul 23.
Selenium–Vitamin E Supplementation in Infertile Men: Effects on Semen Parameters and Pregnancy Rate, Moslemi MK, Tavanbakhsh S Int J Gen Med. 2011 Jan 23;4:99-104.
The Vitamin E–Binding Protein Afamin is Altered Significantly in the Peritoneal Fluid of Women with Endometriosis, Beata E. Seeber, M.D., M.S.C.E., Theresa Czech, M.D.,Hannes Buchner, M.S.,Kurt T. Barnhart, M.D., M.S.C.E.,Christoph Seger, Ph.D.,Guenter, Daxenbichler, Ph.D.,Ludwig Wildt, M.D. and Hans Dieplinger, Ph.D. Fertil Steril. 2010 Dec; 94(7): 2923–2926.
Scientific Opinion on the Substantiation of a Health Claim Related to Increasing Maternal Fo-late Status by Supplemental Folate Intake and Reduced Risk of Neural Tube Defects Pursuant to Article 14 of Regulation (EC) No 1924/2006, EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), accessible at: https://doi.org/10.2903/j.efsa.2013.3328
Calcium L‐methylfolate as a Source of Folate added for Nutritional Purposes to Infant and Fol-low on Formula, Baby Food and Processed Cereal‐based Food, EFSA Journal 2020;18(1):5947, accessible at: https://doi.org/10.2903/j.efsa.2020.5947
Folic Acid Supplementation and Pregnancy: More Than Just Neural Tube Defect Prevention. Greenberg JA, Bell SJ, Guan Y, Yu YH. Rev Obstet Gynecol. 2011 Summer;4(2):52-9. PMID: 22102928; PMCID: PMC3218540.
Thyroid Homeostasis in Mother–Child Pairs in Relation to Maternal Iodine Status: the MISA study, V Berg,T H Nøst, G Skeie, Y Thomassen, B Berlinger, A S Veyhe, R Jorde, J Ø Odland, and S Hansen Eur J Clin Nutr. 2017 Aug; 71(8): 1002–1007.
The WOMED Model of Benign Thyroid Disease: Acquired Magnesium Deficiency Due to Physi-cal and Psychological Stressors Relates to Dysfunction of Oxidative Phosphorylation, Roy Moncayo and Helga Moncayo. BBA Clin. 2015 Jun; 3: 44–64.
Adequately Diversified Dietary Intake and Iron and Folic Acid Supplementation during Pregnancy Is Associated with Reduced Occurrence of Symptoms Suggestive of Pre-Eclampsia or Ec-lampsia in Indian Women, Sutapa Agrawal, Jasmine Fledderjohann, Sukumar Vellakkal, and Da-vid Stuckler. PLoS One. 2015; 10(3): e0119120.
Use of Multivitamins, Intake of B Vitamins and Risk of Ovulatory Infertility, Jorge E. Chavarro, MD, ScD, Janet W. Rich-Edwards, ScD, MPH, Bernard A. Rosner, PhD, and Walter C. Willett, MD, Dr PH. Fertil Steril. 2008 Mar; 89(3): 668–676.
The Role of l-Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation. Virmani MA, Cirulli M. Int J Mol Sci. 2022 Feb 28;23(5):2717. doi: 10.3390/ijms23052717. PMID: 35269860; PMCID: PMC8910660.
The Role of Magnesium and Thyroid Function in Early Pregnancy after In-Vitro Fertilization (IVF): New aspects in endocrine physiology, Sibilla Stuefer, Helga Moncayo, and Roy Moncayo. BBA Clin. 2015 Jun; 3: 196– 204.
Association Between Seminal Plasma Copper and Magnesium Levels with Oxidative Stress in Iraqi Infertile Men, Omar F. Abdul-Rasheed Oman Med J. 2010 Jul; 25(3): 168–17.
Prolonging the female reproductive lifespan and improving egg quality with dietary omega-3 fatty acids, Deepika Nehra, Hau D. Le, Erica M. Fallon, Sarah J. Carlson, Dori Woods, Yvonne A. White, Amy H. Pan, Lankai Guo, Scott J. Rodig, Jonathan L. Tilly, Bo R. Rueda, and Mark Puder. Aging Cell. 2012 Dec; 11(6): 1046–1054.
The effect of omega-3 supplementation on androgen profile and menstrual status in women with polycystic ovary syndrome: A randomized clinical trial, Azadeh Nadjarzadeh, Ph.D. Razieh Dehghani Firouzabadi, M.D., Niloofar Vaziri, M.Sc., Hoorieh Daneshbodi, M.Sc., Mohammad Hassan Lotfi, M.D.,Ph.D., and Hassan Mozaffari-Khosravi, Ph.D. Iran J Reprod Med. 2013 Aug; 11(8): 665–672.
Nutrition and Reproductive Health: Sperm versus Erythrocyte Lipidomic Profile and O-3 Intake, Gabriela Ruth Mendeluk, Mariano Isaac Cohen, Carla Ferreri, and Chryssostomos Chatgili-aloglu. J Nutr Metab. 2015; 2015: 670526.
Prolonging the female reproductive lifespan and improving egg quality with dietary omega-3 fatty acids, Deepika Nehra, Hau D. Le, Erica M. Fallon, Sarah J. Carlson, Dori Woods, Yvonne A. White, Amy H. Pan, Lankai Guo, Scott J. Rodig, Jonathan L. Tilly, Bo R. Rueda, and Mark Puder. Aging Cell. 2012 Dec; 11(6): 1046–1054.
Role of oxidative stress in female reproduction, Agarwal A Gupta S, Sharma RK. Reprod Biol Endocrinol. 2005 Jul 14;3:28.
Expression Patterns and Correlations with Metabolic Markers of Zinc Transporters ZIP14 and ZNT1 in Obesity and Polycystic Ovary Syndrome, Trine Maxel, Pernille Fog Svendsen, Kamille Smidt, Jesper Krogh Lauridsen, Birgitte Brock, Steen Bønlykke Pedersen, Jørgen Rungby, and Agnete Larsen. Front Endocrinol (Lausanne). 2017; 8: 38
Acute dietary zinc deficiency before conception compromises oocyte epigenetic programming and disrupts embryonic development, X Tian and FJ Diaz. Dev Biol. 2013 Apr 1; 376(1): 51–61.
Protective effects of in vitro treatment with zinc, d-aspartate and coenzyme q10 on human sperm motility, lipid peroxidation and DNA fragmentation, Riccardo Talevi, Vincenza Barbato, Ilaria Fiorentino, Sabrina Braun, Salvatore Longobardi, and Roberto Gualtieri. Reprod Biol En-docrinol. 2013; 11: 81.
